Distribution of TSE infectivity in human tissues and body fluids - Annexe A1 and A2 in 'Minimise transmission risk of CJD and vCJD in healthcare settings'

There is evidence that the distribution of the disease-specific partially protease-resistant form of prion protein (PrPTSE) in tissues is more widespread in the body in variant CJD (vCJD) patients than in patients affected by sporadic CJD. The information given in Annex 1 and Annexe 2 describes the position at the time of publication. This will be kept under review and is subject to change as further information becomes available Annexe 1 Distribution of transmissible spongiform encephalopathy infectivity in human tissues and body fluids https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/209759/Annex_A1_-_Distribution_of_TSE_infectivity.pdf Annexe 2 Distribution of infectivity in animal tissue and body fluids https://www.gov.uk/government/uploads/system/uploads/attachment_data/file/209760/Annex_A2_-_Distribution_of_infectivity_in_animal_tissue.pdf