Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK | National Resource for Infection Control (NRIC)

Guidelines for the prophylaxis and treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in the UK

Best practice, Care guideline
Abstract: 
The Department of Health committee (SACAR) asked a joint working party of infection experts to revise previous guidelines on the prevention and control of MRSA infections and to extend the scope to include treatment and prophylaxis of MRSA infections and also laboratory diagnosis & susceptibility testing of MRSA.  One of a set of three, these are the first UK guidelines focussing on the treatment and prophylaxis of MRSA infection. These evidence-based guidelines were produced after an extensive literature review and were further informed by antibiotic susceptibility data on MRSA from the UK. Recommendations are given for the treatment of common infections caused by MRSA, elimination of MRSA from carriage sites and prophylaxis of surgical site infection. There are several antibiotics currently available that are suitable for use in the management of this problem and potentially useful new agents are continuing to emerge.
Authors: 
Curtis G. GemmellDavid I. EdwardsAdam P. FraiseF. Kate GouldGeoff L. RidgwayRod E. Warren and on behalf of the Joint Working Party of the British Society for Antimicrobial ChemotherapyHospital Infection Society and Infection Control Nurses Association
Category: 
Control
Management
Prevention
Treatment

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Summary:
The Department of Health committee (SACAR) asked a joint working party of infection experts to revise previous guidelines on the prevention and control of MRSA infections and to extend the scope to include treatment and prophylaxis of MRSA infections and also laboratory diagnosis & susceptibility testing of MRSA.  One of a set of three, these are the first UK guidelines focussing on the treatment and prophylaxis of MRSA infection. These evidence-based guidelines were produced after an extensive literature review and were further informed by antibiotic susceptibility data on MRSA from the UK. Recommendations are given for the treatment of common infections caused by MRSA, elimination of MRSA from carriage sites and prophylaxis of surgical site infection. There are several antibiotics currently available that are suitable for use in the management of this problem and potentially useful new agents are continuing to emerge. 
Questions Addressed:
These evidence based guidelines provide updated guidance for prophylaxis and treatment of MRSA in the UK.
Type of Study:
Guidelines
Methods Valid:
Yes
Methods Valid Detail:
Results Reliability:
Yes
Problems or Biases:
Relevant Studies:
Keywords:
Methicillin MRSA Guidelines Evidence-Based
Reviewer Name:
Jane Mani-Saada with assistance from Manjit Affley PhD BPharm(Hons) MRPharmS (Senior Scientific Adviser Pfizer Anti-infectives)
Reviewer Post:
Information Assistant
Reviewer Affiliations: