Significant impact of terminal room cleaning with bleach on reducing nosocomial Clostridium difficile

The intervention consisted of replacing quaternary ammonium compound as a room cleaning agent with dilute bleach to disinfect rooms of patients with CDI upon discharge. Results There was a 48% reduction in the prevalence density of C difficile after the bleaching intervention (95% confidence interval: 36%-58%, P < .0001). Conclusion The implementation of a thorough, all-surface terminal bleach cleaning program in the rooms of patients with CDI made a sustained, significant impact on reducing the rate of nosocomial CDI in this health care system.